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李春美,中共党员,女,1973年生,亚洲bet57365游戏大厅三级岗教授,博士,博士生导师。亚洲bet57365游戏大厅教指委主任。获得“教育部新世纪优秀人才”、“ 湖北省杰出青年基金”、获得“华中农业大学教学质量优秀一等奖””,“华中农业大学研究生导师教书育人奖”,“华中农业大学先进女教职工”等荣誉称号;多次被评为华中农业大学“优秀共产党员”。
1991/09-1995/06:亚洲bet57365游戏大厅食品科学专业,学士;1995/09-2000/06:亚洲bet57365游戏大厅农产品加工及贮藏工程专业,博士。
2000/07-2002/12:亚洲bet57365游戏大厅,讲师;2003/01-2010/12:亚洲bet57365游戏大厅,副教授;2009/05-2010/05:美国Miami University,访问学者;2010/12-至今:亚洲bet57365游戏大厅,教授/博导;2018/01-2018/03:美国罗格斯大学(Rutgers University),高级访问学者。
一直致力于植物多酚的研究,研究方向稳定。围绕与植物多酚相关的农产品的采后加工难点,以富含多酚的柿子、茶等为对象,重点针对其加工与高值利用过程中关键性技术难点所涉及的化学结构、活性变化及机制等展开深入研究。主要研究方向有:1.植物多酚提取分离新技术,结构分析,健康调节作用及其分子机制。2. 特色果蔬以及林果精深加工及其高值高效利用新技术研究。3. 功能因子健康挖掘及健康产品开发。
(一)入选的人才计划项目:1. 教育部新世纪优秀人支持计划,NCET-12-0865,“柿子单宁对非酒精性脂肪肝脂质代谢影响机制研究”,2013.1-2015.12,50万元,主持2. 湖北省杰出青年基金,2011CDA108 ,“柿子单宁与其特异靶标蛇毒磷脂酶A2的结合作用及机制”,2012.1-2013.12,10万元,主持3. 武汉市青年科技晨光计划,20065004116-24 ,“莲藕色素前体物质与PPO超分子相互作用及其对莲藕褐变的影响”,2006.1-2008.12, 4.5万元,主持4. 瑞典国际科学基金(IFS),E/3657-1, “Study on the influence of oxidation of tea catechins on the flavor of green tea beverages during a long shelf life”IFS, 2004.1-2005.12,8000美元,主持。(二)主持的其它科研项目1. 国家自然科学基金面上项目“基于脂质筏互作精准解析膳食多酚调节脂质代谢的机制及构效关系”,32172201,58万,主持,2022.1-2025.122. 湖北省重点研发项目“湖北特色浆果功能活性组分绿色制造关键技术研究”,2024BBB034,联合申报,100万,2024-20263. 国家重点研发计划“特色经济林优异种质发掘和精细评价”,2019YFD1000603-1,138万,子课题主持,2019.5-2-2022.124. 国家重点研发计划“特色经济林采后果实与副产物增值加工关键技术研究”,2019YFD1002304,135万,子课题主持,2020.1-2022.125. 2021年创新嘉兴·精英引领“领军人才”创业资助计划C类“天然多元网络抗氧化快速补充运动营养能量棒研发及产业化”,200万元,2022.1-2024.12,主持6. 中央高校基本科研业务费专项资金“基于脂质筏结构破坏和IR结合的柿ECG二聚体抑制脂肪细胞分化的分子机制”,2018.1-2020.12, 24万元,主持。7. 国家自然科学基金面上项目, 31571839 “柿稀有原花青素二聚体通过脂质筏及其上特异受体67LR抑制3T3-L1前脂肪细胞分化的分子机制”,81万元,2016.1-2019.12,主持8. 国家自然科学基金面上项目,31271833 “DP9柿子单宁对其靶标蛋白蛇毒PLA2的特异识别及共价修饰位点研究”,2013.1-2016.12,80万元,主持9. 公益性行业(农业)科研专项经费子课题, 201203047-01,“现代柿产业关键技术研究与试验示范”,2013.1-2016.12,50万元,主持10. 武汉市科技攻关项目,20130205010186,“柿子低温喷雾干燥新技术及系列产品开发”, 2013.1-2014.12,15万元,主持11. 中央高校基本科研业务费专项资金“应季与反季节番茄主要营养、特征风味及代表性活性成分的环境调控研究”,2013-2015,40万元,主持12. 国家“十二五”科技支撑计划“南方特色果蔬食品加工关键技术研究”(子课题),2012-2015,10万元,已结题,主持13. 中央高校基本科研业务费专项资金“柿单宁及其特征结构单元对其特异靶标蛇毒磷脂酶A2结构修饰机制”,2011PY119,2011-2013,15万元,主持14. 国家自然科学基金面上项目,30972398,“柿子提取物解蛇毒关键级分的结构表征及作用机理研究”;2010.1-2012.12,30万,主持15. 教育部科学技术研究重点项目,No.109115,“柿子单宁解蛇毒作用及其构效关系研究”, 2009.1-2011.12,10万元,主持16. 湖北省重大科技攻关计划,2007AA204A01,“淡水鱼蛋白功能食品及废弃物的高效利用技术研究”, 2007.1-2008.12,90万元,主持
【近5年代表性论文】1. Mengyao Zhao, Yunfei Huang, Lin Zhu, Yajie Zhang, Yawei Xu, Yuhan Lu, Kaikai Li, and Chun-mei Li*. A moderately high-fat diet with proper nutrient quality improves glucose homeostasis, hinked to downregulation of intestinal CD36 mediated by the Loss of Desulfovibrio.J. Agric. Food Chem. 2024, 72, 22631−22644 (中科院SCI一区, IF 5.7) 2. Yunfei Huang, Wenqing He, Ruifeng Wang, Yangyang Jia, Lu Li, Yawei Xu, Yuhan Lu, Xiaoxiao Zhang, Feixue Wu, Chunmei Li*. A Simple Method for Preparing Chlorophyll Free Phenols from Olive Leaves and Efciently Enriching it in Refned Olive Oil. Food and Bioprocess Technology https://doi.org/10.1007/s11947-024-03514-w (中科院SCI二区)3. Yunfei Huang, Qingyun Guan, Zhuoya Zhang, Pengxiang Wang, Chunmei Li*. Oleacein: A comprehensive review of its extraction, puriffcation, absorption, metabolism, and health effects. Food Chemistry 433 (2024) 137334 (中科院SCI一区, IF8.5) 4. Pengxiang Wang, Zhuoya Zhang, Kaikai Li and Chunmei Li*.Rapid purification of alkylamides from Zanthoxylum bungeanum by medium-pressure liquid chromatography and the establishment of a numbness prediction model using an electronic tongue. Anal. Methods, 2024, 16, 1196–12055. Zhang yajie, Zhu Lin, Zhao Mengyao, Jia Yangyang, Li Kaikai, Li Chunmei.* The effects of inulin on solubilizing and improving anti-obesity activity of high polymerization persimmon tannin. International Journal of Biological Macromolecules. 2024:270,132232 (中科院SCI一区, IF 7.7) 6. Yangyang Jia, Meizhu Dang, Ibrahim Khalifa, Yajie Zhang, Yunfei Huang, Kaikai Li , Chunmei Li*. Persimmon tannin can enhance the emulsifying properties of persimmon pectin via promoting the network and forming a honeycomb-structure. Food Hydrocolloids 135 (2023) 108157 (中科院SCI一区, IF 11.504) 7.Jia Yangyang; Du Jing; Li Kaikai; Li Chunmei*, Emulsification mechanism of persimmon pectin with promising emulsification capability and stability. Food Hydrocolloids 2022, 131, 107727-107744. (中科院SCI一区, IF 11.504) 8. Hu Yuying; Julian McClements David; Wang Lufeng; Li Chunmei*, Formation and characterization of starch-based spherulite: Effect of molecular weight of potato amylose starch. Food chemistry 2022, 371, 131060. (中科院SCI一区, IF 9.231)9.Hu Yuying; Yu Ben; Wang Lufeng; JulianMcClements David*; Li Chunmei*, Study of dextrin addition on the formation and physicochemical properties of whey protein-stabilized emulsion: Effect of dextrin molecular dimension. Food Hydrocolloids 2022, 128, 107569-107582. (中科院SCI一区, IF11.504)10.Du Jing; Dang Meizhu; Jia Yangyang; Xu Yujuan; Li Chunmei*, Persimmon tannin unevenly changes the physical properties, morphology, subunits composition and cross-linking types of gliadin and glutenin. Food chemistry 2022, 387, 132913-132923. (中科院SCI一区, IF 9.231)11.Jia Yangyang.; Khalifa Ibrahim; Dang Meizhu; Zhang Yajie; Zhu Lin; Zhao Mengyao; Li Kaikai; Li Chunmei*, Confirmation and understanding the potential emulsifying characterization of persimmon pectin: From structural to diverse rheological aspects. Food Hydrocolloids 2022, 131, 107738-107756. (中科院SCI一区, IF 11.504)12. Li Xiaofang; Chen Haoze; JiaYangyang; Peng Jinming; Li Chunmei*. Inhibitory Effects against Alpha-Amylase of an Enriched Polyphenol Extract from Pericarp of Mangosteen (Garcinia mangostana). Foods, 2022, 11 (7), 1001-1018. (中科院SCI 二区, IF 5.561)13. Shen Qiruonan; Zhu Ting; Wu Caie; Xu Yujuan; Li Chunmei*, Ultrasonic-assisted extraction of zeaxanthin from Lycium barbarum L. with composite solvent containing ionic liquid: Experimental and theoretical research. Journal of Molecular Liquids 2022, 347, 118265-118276. (中科院SCI二区, IF 6.633)14.Wang Ruifeng; Zhu Wei; Dang Meizhu; Deng Xiangyi; Shi Xin; Zhang Yajie; Li Kaikai; Li Chunmei*, Targeting Lipid Rafts as a Rapid Screening Strategy for Potential Antiadipogenic Polyphenols along with the Structure–Activity Relationship and Mechanism Elucidation. Journal of Agricultural and Food Chemistry 2022, 70 (12), 3872-3885. (中科院SCI一区, IF 5.895)15. Zhu Ting; Shen Qiruonan; Xu Yujuan; Li Chunmei*, Ionic liquid and ultrasound-assisted extraction of chestnut shell pigment with good hair dyeing capability. Journal of Cleaner Production. 2022, 335, 130195-130205. (中科院SCI一区, IF11.027)16. Jinming Peng, Wenjun Wen, Ruifeng Wang, Kaikai Li, Gengsheng Xiao*, Chunmei Li*. The galloyl moiety enhances the inhibitory activity of polyphenols against the adipogenic differentiation in 3T3-L1 preadipocytes. Food & Function, 2022 : DOI: 10.1039/d1fo04179g (中科院SCI二区, IF6.317)17. Ruifeng Wang , Jinming Peng, Xin Shi, Sijia Cao, Yawei Xu , Gengsheng Xiao*, Chunmei Li*. Change in membrane fluidity induced by polyphenols is highly dependent on the position and number of galloyl groups. BBA - Biomembranes 1864 (2022) 184015(中科院SCI二区, IF4.019)18. Khalifa Ibrahim, Zhu Wei, Nawaz Asad, Li kaikai, Li Chunmei*. Microencapsulated mulberry anthocyanins promote the in vitro-digestibility of whey proteins in glycated energy-ball models. Food Chemistry, 2021, 345: 128805-128816. (中科院SCI一区, IF 7.514)19. Wang Ruifeng, Dang Meizhu, Zhu Wei, Li Chunmei*. Galloyl Group in B-type Proanthocyanidin Dimers Was Responsible for Its Differential Inhibitory Activity on 3T3-L1 Preadipocytes due to the Strong Lipid Raft-Perturbing Potency[J]. Journal of Agricultural and Food Chemistry, 2021, 69(17): 5216-5225. (中科院SCI一区, IF 5.279)20. Khalifa Ibrahim, Du Jing, Nawaz Asad, Li Chunmei*. Multiple co‐pigments of quercetin and chlorogenic acid blends intensify the color of mulberry anthocyanins: insights from hyperchromicity, kinetics, and molecular modeling investigations [J]. Journal of the Science of Food and Agriculture, 2021, 101(4):1579-1588. (中科院SCI二区, IF 3.638)21. Hu Yuying, Julian McClements David, Wang Lufeng, Li Chunmei*. Formation and characterization of starch-based spherulite: Effect of molecular weight of potato amylose starch. Food Chemistry. 2021, 371:131060-123069. (中科院SCI一区, IF 7.514)22. Ruifeng Wang, Ibrahim Khalifa, Xia Du, Kaikai Li, Yujuan Xu, Li Chunmei*. Effects of anthocyanins on beta-lactoglobulin glycoxidation: a study of mechanisms and structure-activity relationship. Food & Function. 2021,12(21):10550-10562 (中科院SCI二区, IF 5.396)23. Du Jing, Dang Meizhu, Khalifa Ibrahim, Du Xia, Xu Yujuan, Li Chunmei*. Persimmon tannin changes the properties and the morphology of wheat gluten by altering the cross-linking, and the secondary structure in a dose-dependent manner. Food Research International, 2020, 137:109536. (中科院SCI一区, IF 6.475)24. Khalifa Ibrahim, Zhu Wei, Mohammed Hammad Hamed Hammad, Dutta Kunal, Chunmei Li*. Tannins inhibit SARS‐CoV‐2 through binding with catalytic dyad residues of 3CLpro: An in silico approach with 19 structural different hydrolysable tannins. Journal of food biochemistry, 2020, 44(10): e13432. (中科院SCI三区, IF 2.720)25. Zhu Wei, Khalifa Ibrahim, Wang Ruifeng, Chunmei Li*. Persimmon highly galloylated‐tannins in vitro mitigated α‐amylase and α‐glucosidase via statically binding with their catalytic‐closed sides and altering their secondary structure elements. Journal of food biochemistry, 2020, 44(7): e13234. (中科院SCI三区, IF 2.720)26. Chen Jinyu, Du Jing, Li Mengli, Chunmei Li*. Degradation kinetics and pathways of red raspberry anthocyanins in model and juice systems and their correlation with color and antioxidant changes during storage. LWT-Food science and technology, 2020, 128:109448. (中科院SCI一区, IF 4.952)27. Khalifa Ibrahim, Xia Du, Dutta Kunal, Peng Jinming, Jia Yangyang, Chunmei Li*. Mulberry anthocyanins exert anti-AGEs effects by selectively trapping glyoxal and structural-dependently blocking the lysyl residues of β-lactoglobulins. Bioorganic chemistry, 2020, 96:103615. (中科院SCI二区, IF 5.275)28. Li Jin, Zeng Jian, Peng Jinming, Jia Yangyang, Chunmei Li*. Simultaneous determination of the pharmacokinetics of A-type EGCG and ECG dimers in mice plasma and its metabolites by UPLC-QTOF-MS. International journal of food sciences and nutrition, 2020, 71(2): 211-220. (中科院SCI三区, IF 3.833)29. Wang Ruifeng, Zhu Wei, Peng Jinming, Li Kaikai, Chunmei Li*. Lipid rafts as potential mechanistic targets underlying the pleiotropic actions of polyphenols. Critical Reviews in Food Science and Nutrition,2022,62:2, 311-324, DOI: 10.1080/10408398.2020.181517130. Wei Zhu, Ruifeng Wang, Khalifa, Ibrahim and Chunmei Li*, Understanding toward the Biophysical Interaction of Polymeric Proanthocyanidins (Persimmon Condensed Tannins) with Biomembranes: Relevance for Biological Effects,Journal of Agricultural and Food Chemistry, 2019,67,11044-11052(中科院SCI一区,IF 3.571)31. .Jing Du, Fen Yao, Mengying Zhang, Ibrahim Khalifa, Kaikai Li, and ChunMei Li*. Effect of persimmon tannin on the physicochemical properties of maize starch with different amylose/amylopectin ratios, International Journal of Biological Macromolecules, 2019,132:1193-1199(中科院SCI三区,IF 4.784)32. Jinming Peng, Kaikai Li, Wei Zhu, Rongzu Nie, Ruifeng Wang, and ChunMei Li*, Penta-O-galloyl-beta-D-glucose, a hydrolysable tannin from Radix Paeoniae Alba, inhibits adipogenesis and TNF-alpha-mediated inflammation in 3T3-L1 cells, Chemical biological interactions, 2019,302,156-163(中科院SCI三区,IF 3.407)33. Rongzu Nie, Meizhu Dang , Kaikai Li, Jinming Peng, Jing Du, Mengying Zhang, and ChunMei Li*, A-type EGCG dimer, a new proanthocyanidins dimer from persimmon fruits, interacts with the amino acid residues of A beta(40) which possessed high aggregation-propensity and strongly inhibits its amyloid fibrils formation,Journal of Functional Foods, 2019, 52, 492-504(中科院SCI二区,IF 3.197)
【专利】1. 李春美,万琼红,熊善柏,钟朝晖,党美珠.从淡水鱼鱼鳞中制备未变性胶原蛋白的方法, ZL200810048018.32. 李春美; 杨立; 邹波; 杜静, 一种抗氧化补钙鱼鳞肽钙复合咀嚼片及其制备方法, ZL201210010943.33. 李春美; 杜静; 葛珍珍; 徐泽; 朱维,一种柿子全果低温喷雾干燥粉及其制备方法,ZL2014101900840.94. 李春美,吴思,李凯凯,邓祥宜,彭进明. 一种柿子山楂果酱及其制备方法,ZL201710213858.X5. 李春美,沈齐若楠,朱婷. 一种提取枸杞中玉米黄素的方法和应用。ZL202110620722.76. 李春美,彭进明,刘滔,王冬林,徐泽.一种柿子全果果糕及制造方法与品质检测,申请号:CN201410500301.07. 李春美,朱婷,沈齐若楠. 一种提取板栗壳中板栗色素的方法和在染发剂中的应用。ZL202110706697.48. 李春美; 王玥; 李凯凯; 杨明美; 邓祥宜, 一种柿果乳酸菌发酵果汁饮料制备方法, 申请号:CN2017010601.3243909. 李春美,易卜拉欣•哈里发,贾洋洋,一种掺入微胶囊化桑葚多酚的能量球的制作方法,申请号:CN201811418181.410. 李春美,李凯凯,石鑫,张亚杰,王瑞丰,徐金帅,贾洋洋.一种柿子低聚原花青素的制备方法及其应用,申请号:CN202010019052.911. 李春美,王瑞丰,朱维,一种抗肥胖活性化合物的筛选方法,申请号:CN202010709429.312. 李春美,杜霞,李凯凯, 朱琳,一种具有抗糖功效的组合物及其应用,申请号:CN202010749801.313. 李春美,李凯凯,张亚杰,侯焘,李晓芳,陈平,余颖.一种高聚原花青素的增溶方法及其制得的复合物和应用,申请号:CN202011464022.514. 李春美,贺婷.一种富含玉米黄素杏仁油的组合物及其应用,申请号:CN202110522818.X15. 李春美,李凯凯,刘渝.一种复合谷物坚果能量棒及其制作方法, 申请号:CN202110681717.7【科技奖励和鉴定成果】1. 2021年,传统果干蜜饯现代化加工关键技术及产业化“,获得中国轻工业联合会科学技术进步奖一等奖(排名第4,编号2021-J-2-12)2. 2019年,“特色浆果的营养健康效应及其精深加工关键技术研究与应用”,获广东省科技进步一等奖(排名第3,3/15,编号J03-1-01-R03)3. 2019年,“亚热带特色水果高效加工及产业化”,获中国产学研合作创新成果奖一等奖(排名第6,编号20199056)4. 2018年,“岭南大宗水果综合加工关键技术及产业化应用”,获广东省科技进步一等奖(排名第6,编号B03-1-01-R06)5. 2017年,获中华人民共和国农业部科技进步二等奖(排名第6)6. 2017年,获神农中华农业科技奖(排名第6)7. 李春美(6/24), 华南特色水果综合加工关键技术及产业化, 中华人民共和国农业部, 科技进步, 省部二等奖, 2017.11.17(徐玉娟; 肖更生; 吴继军; 余元善; 唐道邦; 李春美; 温靖; 张岩; 陈卫东; 宁进辉;李兴斌; 林羡; 陈于陇; 李俊; 黄盛锋; 卫高利; 张友胜; 刘子放; 李升锋; 刘学铭; 傅曼琴; 邹波; 安可婧; 姚锡镇)证书编号:KJ2017-R2-033-068. 李春美,杜静,李凯凯. “柿果全粉高效制备关键技术研究”,通过湖北省科技厅组织的成果鉴定,鉴定结果:国际先进;2017.1
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